{"id":65949,"date":"2018-11-30T15:39:07","date_gmt":"2018-11-30T15:39:07","guid":{"rendered":"https:\/\/news.microsoft.com\/?p=427869"},"modified":"2018-11-30T15:39:07","modified_gmt":"2018-11-30T15:39:07","slug":"princeton-and-microsoft-collaborate-to-tackle-fundamental-challenges-in-microbiology","status":"publish","type":"post","link":"https:\/\/sickgaming.net\/blog\/2018\/11\/30\/princeton-and-microsoft-collaborate-to-tackle-fundamental-challenges-in-microbiology\/","title":{"rendered":"Princeton and Microsoft collaborate to tackle fundamental challenges in microbiology"},"content":{"rendered":"<p>Princeton University has teamed up with Microsoft to collaborate on the leading edge of microbiology and computational modelling research.\u00a0\u00a0\u00a0<\/p>\n<p>In this project, Microsoft is helping Princeton to better understand the mechanisms of biofilm formation by providing advanced technology that will greatly extend the type of research analysis capable today. Biofilms \u2014 surface-associated communities of bacteria \u2014 are the leading cause of microbial infection worldwide and kill as many people as cancer does. They are also a leading cause of antibiotic resistance, a problem highlighted by the World Health Organization as \u201ca global crisis that we cannot ignore.\u201d Understanding how biofilms form could enable new strategies to disrupt them.\u00a0<\/p>\n<article class=\"view-mode-right-third media media-image\">\n<div class=\"field field--name-image field--type-image field--label-hidden field__item\"><img decoding=\"async\" src=\"http:\/\/www.sickgaming.net\/blog\/wp-content\/uploads\/2018\/12\/princeton-and-microsoft-collaborate-to-tackle-fundamental-challenges-in-microbiology.jpg\" alt=\"Ned Wingreen\" \/><\/div>\n<div class=\"image-caption\">\n<div class=\"field field--name-field-media-caption field--type-text-long field--label-hidden field__item\">\n<p>Ned Wingreen,\u00a0the Howard A. Prior Professor in the Life Sciences and professor of molecular biology and the\u00a0Lewis-Sigler Institute for Integrative Genomics.<\/p>\n<\/div>\n<div class=\"image-byline\">\n<p>Photo by<\/p>\n<div class=\"field field--name-field-byline field--type-entity-reference field--label-hidden field__items\">\n<div class=\"field__item\">\n<div>\n<p>Denise Applewhite, Office of Communications<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/article>\n<p>To support Princeton, a Microsoft team led by <a href=\"https:\/\/www.microsoft.com\/en-us\/research\/people\/aphillip\/\">Dr.\u00a0Andrew Phillips<\/a>, head of the Biological Computation group at <a href=\"https:\/\/www.microsoft.com\/en-us\/research\/\">Microsoft Research<\/a>, will be working closely with Bonnie Bassler, a global pioneer in microbiology who is\u00a0the Squibb Professor in Molecular Biology and chair of the\u00a0<a href=\"https:\/\/molbio.princeton.edu\/\">Department of Molecular Biology<\/a>\u00a0at Princeton\u00a0and\u00a0a Howard Hughes Medical Institute Investigator,\u00a0and with Ned Wingreen,\u00a0the Howard A. Prior Professor in the Life Sciences and professor of molecular biology and the\u00a0<a href=\"https:\/\/lsi.princeton.edu\/\">Lewis-Sigler Institute for Integrative Genomics<\/a>.<\/p>\n<p>Using the power of Microsoft\u2019s cloud and advanced machine learning, Princeton will be able to study different strains of biofilms in new ways to better understand how they work. Microsoft is contributing a cloud-based prototype that can be used for biological modelling and experimentation that will be deployed at Princeton.\u00a0This work combines programming languages and compilers, which generate biological protocols that can be executed using lab automation technology. It allows experimental data to be uploaded to the cloud where it can be analyzed at scale using advanced machine learning and data analysis methods, to generate biological knowledge. This in turn informs the design of subsequent experiments, to provide insight into the mechanisms of biofilm formation.\u00a0Princeton is contributing world-leading expertise in experiments and modelling of microbial biofilms.\u00a0\u00a0<\/p>\n<p>\u201cThis collaboration enables us to bring together advances in computing and microbiology in powerful new ways,\u201d said Brad Smith, president of Microsoft. \u201cThis partnership can help us unlock answers that we hope someday may help save millions of people around the world.\u201d<\/p>\n<p>\u201cBy combining our distinctive strengths, Princeton and Microsoft will increase our ability to make the discoveries needed to improve lives and serve society,\u201d said Christopher L. Eisgruber, president of Princeton University. \u201cTechnology is creating new possibilities for collaboration, and we hope this venture will inspire other innovative partnerships in the years ahead.\u201d<\/p>\n<p>Pablo Debenedetti, Princeton\u2019s\u00a0<a href=\"https:\/\/www.princeton.edu\/research\/office-dean-research\">dean for research<\/a>,\u00a0said: \u201cWe are delighted to be collaborating with Microsoft to advance scientific innovation with this new project, investigating the fundamentals that underlie urgent biomedical problems. Doing cutting-edge research that helps define the boundaries of knowledge and that could ultimately benefit society at large is what we strive for at Princeton.\u201d<\/p>\n<p>Princeton\u2019s relationship with Microsoft is one of the University\u2019s most extensive with industry, spanning collaborations in computer science, cybersecurity and now biomedical research.<\/p>\n<p>As a global research university and leader in innovation, Princeton University cultivates mutually beneficial relationships with companies to support the University\u2019s educational, scientific and scholarly mission. The University is guided by the principle that initiatives to fortify and connect with the innovation ecosystem will advance Princeton\u2019s role as an internationally renowned institution of higher education and accelerate its ability to have greater impact in the world.\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Princeton University has teamed up with Microsoft to collaborate on the leading edge of microbiology and computational modelling research.\u00a0\u00a0\u00a0 In this project, Microsoft is helping Princeton to better understand the mechanisms of biofilm formation by providing advanced technology that will greatly extend the type of research analysis capable today. Biofilms \u2014 surface-associated communities of bacteria [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":65950,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[49],"tags":[159,50],"class_list":["post-65949","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-microsoft-news","tag-microsoft-research","tag-recent-news"],"_links":{"self":[{"href":"https:\/\/sickgaming.net\/blog\/wp-json\/wp\/v2\/posts\/65949","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sickgaming.net\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sickgaming.net\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sickgaming.net\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/sickgaming.net\/blog\/wp-json\/wp\/v2\/comments?post=65949"}],"version-history":[{"count":0,"href":"https:\/\/sickgaming.net\/blog\/wp-json\/wp\/v2\/posts\/65949\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sickgaming.net\/blog\/wp-json\/wp\/v2\/media\/65950"}],"wp:attachment":[{"href":"https:\/\/sickgaming.net\/blog\/wp-json\/wp\/v2\/media?parent=65949"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sickgaming.net\/blog\/wp-json\/wp\/v2\/categories?post=65949"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sickgaming.net\/blog\/wp-json\/wp\/v2\/tags?post=65949"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}